HCID 14468512, compound → HCID 86724002, compound

HRID 1475393Notes

Reaction equation

HRID 1475393 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([NH2:8])[C:5]([I:9])=[CH:4][N:3]=1.Br[CH2:11][C:12](=[CH2:22])[CH2:13][O:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:15]([O:14][CH2:13][C:12](=[CH2:11])[CH2:22][NH:8][C:6]1[C:5]([I:9])=[CH:4][N:3]=[C:2]([Cl:1])[CH:7]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 14468512HCID 14468512, compoundHCID 454803662-Chloro-5-iodopyridin-4-amine

Product 1

HCID 86724002HCID 86724002, compound

Conditions

Temperature
55 °C

Procedure

The title compound was prepared from 2-chloro-5-iodo-pyridin-4-yl-amine and (2-bromomethyl-allyloxymethyl)-benzene following a similar method to that described in Preparation 108. The reaction was stirred at 55° C. for 3 h. MS: [M+H]+=415.

Workup

  1. customthat described in Preparation 108

Sources & evidence

ORD record
ord-24206a5c22a945628e7ec581af43ffa1
Source dataset
uspto-grants-2015_04
Patent number
US09018214B2

Reaction notes

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