HCID 70980896, compound → HCID 70981443, compound

HRID 1475412Notes

Reaction equation

HRID 1475412 reaction equation
[C:1]([O:5][C:6]([N:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14](Cl)[CH:15]=2)[C:10]([CH3:19])([CH3:18])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[Cl-].[CH3:21][Zn+]>>[C:1]([O:5][C:6]([N:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([CH3:21])[CH:15]=2)[C:10]([CH3:19])([CH3:18])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 70980896HCID 70980896, compoundHCID 178477797HCID 178477797, compound

Product 1

HCID 70981443HCID 70981443, compound

Procedure

The title compound was prepared from 6-chloro-3,3-dimethyl-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester and methylzinc chloride following similar methods to those described in Preparation 117, MS: [M+H]+=206 (-tBu).

Workup

  1. customthose described in Preparation 117, MS

Sources & evidence

ORD record
ord-1303bdd04c0b4c12af8c699cc589f621
Source dataset
uspto-grants-2015_04
Patent number
US09018214B2

Reaction notes

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