Acetyl chloride → HCID 70980521, compound

Participants

Reaction Steps

Acetyl chloride (163 μL, 2.29 mmol) and TEA (313 μL, 2.29 mmol) were added to a solution of 6-bromo-3-methyl-3-phenyl-2,3-dihydro-1H-indole (600 mg, 2.1 mmol) in DCM (20 mL) at 0° C. The reaction was stirred for 45 minutes at room temperature and then quenched with 1 M aqueous HCl and extracted with EtOAc. The organic phase was dried over MgSO4 and concentrated in vacuo to give the title compound (660 mg) as a yellow solid. MS: [M+H]+=330.

Provenance & Evidence