Diethyl Ether → HCID 70981313, compound

Participants

Reaction Conditions

Reaction Steps

CuCN (179 mg, 2 mmol) was added to a solution of 1-(6-bromo-3-methyl-3-phenyl-2,3-dihydro-indol-1-yl)-ethanone (330 mg, 1 mmol) in NMP (5 mL). The reaction was stirred at 175° C. for 16 h. Et2O was added to the mixture and the solid was filtered off. The filtrate was washed with 2 M aqueous HCl and saturated aqueous NaHCO3. The solvent was removed in vacuo to give the title compound (250 mg) as a brown solid. MS: [M+H]+=277.

Provenance & Evidence