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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1475487Generated: October 31, 2026

HCID 86724034, compound → HCID 70980573, compound

https://huagongshe.com/reaction/1475487

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86724034HCID 86724034—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 70980573HCID 7098057392%

Reaction Steps

To a solution of (2R,5R)-4-[2-(6-cyclohex-1-enyl-3,3-dimethyl-2,3-dihydro-pyrrolo[3,2-c]pyridin-1-yl)-2-oxo-ethyl]-5-methoxymethyl-2-methyl-piperazine-1-carboxylic acid tert-butyl ester (see Table 1) (65 mg, 0.13 mmol) in EtOH (5 mL)was added palladium on carbon (10%, 20 mg) and the mixture was hydrogenated for 2 h. The catalyst was filtered and the filtrate evaporated to afford the title compound (60 mg, 92%) as a white solid. MS: [M+H]+=515.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09018214B2
Source datasetuspto-grants-2015_04
ORD IDord-88c19fb8237746d1b75c30abed856857
Source noteuspto-grants-2015_04