Thiophene-3-boronic acid → HCID 70980626, compound

HRID 1475489Notes

Reaction equation

HRID 1475489 reaction equation
[C:1]([O:5][C:6]([N:8]1[C:16]2[CH:15]=[C:14](Cl)[N:13]=[CH:12][C:11]=2[C:10]([CH3:19])([CH3:18])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[S:20]1[CH:24]=[CH:23][C:22](B(O)O)=[CH:21]1>>[C:1]([O:5][C:6]([N:8]1[C:16]2[CH:15]=[C:14]([C:22]3[CH:23]=[CH:24][S:20][CH:21]=3)[N:13]=[CH:12][C:11]=2[C:10]([CH3:19])([CH3:18])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 581760Thiophene-3-boronic acidHCID 86723969tert-Butyl 6-chloro-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate

Product 1

HCID 70980626HCID 70980626, compound

Procedure

Prepared from 6-chloro-3,3-dimethyl-2,3-dihydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester and thiophen-3-boronic acid using a procedure similar to Prep 379. MS [M+H]+ 331.

Sources & evidence

ORD record
ord-38c666af057e4b7fa81d0991e8019e34
Source dataset
uspto-grants-2015_04
Patent number
US09018214B2

Reaction notes

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