4,4,5,5-Tetramethyl-2-(5-methylthiophen-2-yl)-1,3,2-dioxaborolane → HCID 70981644, compound

HRID 1475493Notes

Reaction equation

HRID 1475493 reaction equation
[C:1]([O:5][C:6]([N:8]1[C:16]2[CH:15]=[C:14](Cl)[N:13]=[CH:12][C:11]=2[C:10]([CH3:19])([CH3:18])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].CC1(C)C(C)(C)OB([C:28]2[S:29][C:30]([CH3:33])=[CH:31][CH:32]=2)O1>>[C:1]([O:5][C:6]([N:8]1[C:16]2[CH:15]=[C:14]([C:28]3[S:29][C:30]([CH3:33])=[CH:31][CH:32]=3)[N:13]=[CH:12][C:11]=2[C:10]([CH3:19])([CH3:18])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 118169404,4,5,5-Tetramethyl-2-(5-methylthiophen-2-yl)-1,3,2-dioxaborolaneHCID 86723969tert-Butyl 6-chloro-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate

Product 1

HCID 70981644HCID 70981644, compound

Procedure

Prepared from 6-chloro-3,3-dimethyl-2,3-dihydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester and 4,4,5,5-tetramethyl-2-(5-methyl-thiophen-2-yl)-[1,3,2]dioxaborolane using a procedure similar to Preparation 379. MS: [M+H]+=345.

Workup

  1. customsimilar to Preparation 379

Sources & evidence

ORD record
ord-c7593bdc0e3943dd9d7310cb34352d13
Source dataset
uspto-grants-2015_04
Patent number
US09018214B2

Reaction notes

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