N-methoxy-N-methylcyclobutanecarboxamide → HCID 70980886, compound

HRID 1475501Notes

Reaction equation

HRID 1475501 reaction equation
[C:1]([O:5][C:6]([N:8]1[C:16]2[C:11](=[N:12][CH:13]=[C:14](Br)[CH:15]=2)[C:10]([CH3:19])([CH3:18])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].CON(C)[C:23]([CH:25]1[CH2:28][CH2:27][CH2:26]1)=[O:24]>>[C:1]([O:5][C:6]([N:8]1[C:16]2[C:11](=[N:12][CH:13]=[C:14]([C:23]([CH:25]3[CH2:28][CH2:27][CH2:26]3)=[O:24])[CH:15]=2)[C:10]([CH3:19])([CH3:18])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 45084194N-methoxy-N-methylcyclobutanecarboxamideHCID 70980192HCID 70980192, compound

Product 1

HCID 70980886HCID 70980886, compound

Procedure

Prepared from 6-bromo-3,3-dimethyl-2,3-dihydro-pyrrolo[3,2-b]pyridine-1-carboxylic acid tert-butyl ester and cyclobutanecarboxylic acid methoxy-methyl-amide using a procedure analogous to that of Preparation 263. MS: [M+H]+=331.

Workup

  1. customof Preparation 263

Sources & evidence

ORD record
ord-cc60af9194244e5db4b5c0c566b0fe0f
Source dataset
uspto-grants-2015_04
Patent number
US09018214B2

Reaction notes

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