(Pyrimidin-5-yl)boronic acid → N,N-dibenzyl-5-pyrimidin-5-yl-3,4-dihydro-2H-chromen-3-amine

HRID 147551Notes

Reaction equation

HRID 147551 reaction equation
[F:10][C:11]([F:12])([F:13])[S:14]([O:15][c:16]1[c:17]2[c:22]([cH:23][cH:24][cH:25]1)[O:21][CH2:20][CH:19]([N:26]([CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[CH2:34][c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1)[CH2:18]2)(=[O:41])=[O:42].[n:1]1[cH:2][n:3][cH:4][c:5]([B:7]([OH:8])[OH:9])[cH:6]1>>[n:1]1[cH:2][n:3][cH:4][c:5](-[c:16]2[c:17]3[c:22]([cH:23][cH:24][cH:25]2)[O:21][CH2:20][CH:19]([N:26]([CH2:27][c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[CH2:34][c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[CH2:18]3)[cH:6]1

Participants

3

Reactant 2

HCID 2795193(Pyrimidin-5-yl)boronic acidHCID 74421935[3-(dibenzylamino)-3,4-dihydro-2H-chromen-5-yl] trifluoromethanesulfonate

Product 1

HCID 140551732N,N-dibenzyl-5-pyrimidin-5-yl-3,4-dihydro-2H-chromen-3-amine

Sources & evidence

ORD record
ord-29a87062da214e6db8fe2d7036af76c0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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