Hydrochloric Acid → HCID 67078348, compound

Participants

Reaction Steps

316.5 mg (7.9 mmol) of sodium hydroxide were added to a solution of 192.5 mg (0.79 mmol) of (+/−)-methyl(4-cyanophenyl)(cyclopentyl)acetate in 1.7 ml of THF/methanol (1:1), and the mixture was stirred at RT for 3 h. The reaction mixture was then poured into water, neutralized with 1 N hydrochloric acid and extracted with ethyl acetate. The organic phase was dried over magnesium sulphate and concentrated. This gave 125.6 mg (69% of theory) of the title compound.

Provenance & Evidence