HCID 67957891, compound → HCID 67958075, compound

Participants

Reaction Steps

224 mg (0.76 mmol) of methyl 1-[1-(4-chloro-3-nitrophenyl)propyl]cyclopropanecarboxylate were dissolved in 48 ml of ethyl acetate, the mixture was inertized with argon and 40 mg of palladium (10% on carbon) were added. At RT, the reaction mixture was stirred under an atmosphere of hydrogen at atmospheric pressure for a total of 24 h. The mixture was then filtered through Celite, the residue was washed thoroughly with ethyl acetate and the combined filtrate was concentrated under reduced pressure. This gave 195 mg of the target compound (96% of theory).

Provenance & Evidence