HCID 67076259, compound → HCID 67169932, compound

HRID 1475698Notes

Reaction equation

HRID 1475698 reaction equation
[CH3:1][O:2][C:3]([C:5]1([NH:13][C:14]([O:16]CC2C=CC=CC=2)=O)[CH2:11][CH2:10][CH2:9][C:8](=[O:12])[CH2:7][CH2:6]1)=[O:4].[CH3:24][O:25][C:26]1[CH:34]=[CH:33][C:29](C(O)=O)=[CH:28][C:27]=1[O:35][CH2:36][CH2:37][C:38]1[CH:39]=[C:40]([CH3:44])[CH:41]=[CH:42][CH:43]=1>>[CH3:1][O:2][C:3]([C:5]1([NH:13][C:14](=[O:16])[C:29]2[CH:33]=[CH:34][C:26]([O:25][CH3:24])=[C:27]([O:35][CH2:36][CH2:37][C:38]3[CH:39]=[C:40]([CH3:44])[CH:41]=[CH:42][CH:43]=3)[CH:28]=2)[CH2:11][CH2:10][CH2:9][C:8](=[O:12])[CH2:7][CH2:6]1)=[O:4]

Participants

3

Reactant 2

HCID 67076259HCID 67076259, compoundHCID 67170265HCID 67170265, compound

Product 1

HCID 67169932HCID 67169932, compound

Procedure

1-Benzyloxycarbonylamino-4-oxo-cycloheptanecarboxylic acid methyl ester was hydrogenated in analogy to step 3 of example 51 and transformed into the title compound by reaction with 4-methoxy-3-(2-m-tolyl-ethoxy)-benzoic acid in analogy to step 3 of example 1.

Sources & evidence

ORD record
ord-ad8217fad7344deda810b1ac98c744b5
Source dataset
uspto-grants-2015_04
Patent number
US09018383B2

Reaction notes

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