反应详情

4-Chloro-3-hydroxybenzoic acid (1.00 g, 5.80 mmol) was suspended in acetic anhydride (11 ml) and heated to reflux for 3 h. After cooling, water (11 ml) was added and the mixture was refluxed again for 1 h. After cooling, crystals formed overnight which were collected by suction filtration and dried in vacuo to yield the title compound (630 mg).

1. temperatureheated
2. temperatureto reflux for 3 h
3. temperatureAfter cooling
4. temperaturethe mixture was refluxed again for 1 h
5. temperatureAfter cooling
6. customcrystals formed overnight which
7. filtrationwere collected by suction filtration
8. customdried in vacuo