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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1475712Generated: November 1, 2026

3-Methylbenzeneethanol → 1-[4-Chloro-3-(2-m-tolyl-ethoxy)-benzoylamino]-cycloheptanecarboxylic acid

https://huagongshe.com/reaction/1475712

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethylbenzeneethanolHCID 74648—
Reactant1-(4-Chloro-3-hydroxy-benzoylamino)-cycloheptanecarboxylic acid methyl esterHCID 67170384—
Product1-[4-Chloro-3-(2-m-tolyl-ethoxy)-benzoylamino]-cycloheptanecarboxylic acidHCID 67170064—

Reaction Steps

The compound of step 3 was etherified with 2-m-tolylethanol in analogy to step 1 of example 1, and the intermediate was hydrolyzed in analogy to step 4 of example 1 to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09018383B2
Source datasetuspto-grants-2015_04
ORD IDord-8a953abef0d842a0836190265e47070d
Source noteuspto-grants-2015_04