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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1475762Generated: October 25, 2026

m-Chlorophenethylic alcohol → 5-[2-(3-Chloro-phenyl)-ethoxy]-nicotinic Acid Ethyl Ester

https://huagongshe.com/reaction/1475762

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-Chlorophenethylic alcoholHCID 78856—
ReactantEthyl 5-hydroxynicotinateHCID 910016—
Product5-[2-(3-Chloro-phenyl)-ethoxy]-nicotinic Acid Ethyl EsterHCID 67169864—

Reaction Steps

5-Hydroxy-nicotinic acid ethyl ester and 2-(3-chlorophenyl)ethanol were etherified in a Mitsunobu reaction in analogy to step 3 of example 3 to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09018383B2
Source datasetuspto-grants-2015_04
ORD IDord-45c86d0823cc4debaf12e6a718573bdf
Source noteuspto-grants-2015_04