Ethyl Acetate → HCID 67170012, compound

Participants

Reaction Steps

1.4 g of 4-(3,3-Difluoro-cyclobutoxy)-3-nitro-benzoic acid methyl ester were dissolved using 50 ml of EA and 10 ml of acetic acid, 200 mg of Pd/C 10% (50% water) added and hydrogenated under an atmosphere of hydrogen at normal pressure for 16 h at room temperature. The reaction mixture was filtrated, 100 ml of EA added and washed twice using 30 ml of a saturated aqueous Na2CO3-solution. The organic layer was dried using MgSO4 and volatiles were evaporated to yield 1.0 g of the title compound that was used without further purification.

Provenance & Evidence