Sulfuric Acid → HCID 68275986, compound

Participants

Reaction Steps

Diethyl 5-(diisopentylcarbamoyl)pyrazolo[1,5-a]pyridine-2,3-dicarboxylate (0.35 g, 0.786 mmol) was added to 40% aqueous sulphuric acid (5 ml) and stirred at reflux for 3 h. The resulting suspension was cooled in an ice bath then extracted with ethyl acetate (3×25 ml). The combined organic layers were washed with brine and concentrated to afford, 0.29 g (98%) of the title compound as a white solid. LCMS m/z 346.2 (M+H)+. ret. time=2.57 min.

Provenance & Evidence