HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → (Acetyloxy)-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | tert-butyl N-hydroxycarbamate | HCID 97534 | — |
| Product | (Acetyloxy)-carbamic acid tert-butyl ester | HCID 10058028 | — |
Reaction Steps
[(tert-Butoxy)carbonyl]amino acetate is prepared from acetyl chloride and N-tert-butoxycarbonyl hydroxylamine according to Scheme 1 and the method described by Carpino et al. J. Am. Chem. Soc. 1959, 955-957. (10 g, 100%), 1H NMR (500 MHz, DMSO-d6) δ ppm 10.57 (1H, br. s.), 2.10 (3H, s), 1.41 (9H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09018411B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-d05cb9b782534d2183f65ac043b75006 |
| Source note | uspto-grants-2015_04 |