HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 53241284, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | [(tert-Butoxy)carbonyl]amino 2,2-dimethylpropanoate | HCID 300008 | — |
| Reactant | 5-Chlorothiophene-2-sulfonyl chloride | HCID 2733925 | — |
| Product | HCID 53241284 | HCID 53241284 | — |
Reaction Steps
N-[(tert-Butoxy)carbonyl]-5-chlorothiophene-2-sulfonamido 2,2-dimethylpropanoate (74) is synthesised from 5-chlorothiophene sulfonyl chloride, sodium hydride and [(tert-butoxy)carbonyl]amino 2,2-dimethylpropanoate according to Scheme 2. (1.89 g, 100%), 1H NMR (500 MHz, CHLOROFORM-d) δ ppm 7.65 (1H, d, 4.1 Hz), 6.99 (1H, d, 4.1 Hz), 1.48 (9H, s), 1.35 (9H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09018411B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-1d965dda61634bf995b03dcf87f44711 |
| Source note | uspto-grants-2015_04 |