HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 53241380, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | [(tert-Butoxy)carbonyl]amino 2,2-dimethylpropanoate | HCID 300008 | — |
| Reactant | Pyridine-3-sulfonyl chloride | HCID 3164136 | — |
| Product | HCID 53241380 | HCID 53241380 | — |
Reaction Steps
N-[(tert-Butoxy)carbonyl]pyridine-3-sulfonamido 2,2-dimethylpropanoate (77) is synthesised from 3-pyridine sulfonyl chloride, sodium hydride and [(tert-butoxy)carbonyl]amino 2,2-dimethylpropanoate according to Scheme 2. (0.99 g, 58%), 1H NMR (500 MHz, CHLOROFORM-d) δ ppm 9.16-9.26 (1H, m), 8.89 (1H, d, 4.4 Hz), 8.36 (1H, d, 8.2 Hz), 7.54 (1H, dd, 8.2, 4.9 Hz), 1.42 (9H, s), 1.37 (9H, s)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09018411B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-d9633eefe11b4f72811abd73e18faccb |
| Source note | uspto-grants-2015_04 |