HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 53241381, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Pyridine-3-sulfonyl chloride | HCID 3164136 | — |
| Reactant | HCID 57211324 | HCID 57211324 | — |
| Product | HCID 53241381 | HCID 53241381 | — |
Reaction Steps
N-[(tert-Butoxy)carbonyl]pyridine-3-sulfonamido 2-methylpropanoate (111) is synthesised from 3-pyridine sulfonyl chloride, sodium hydride and [(tert-butoxy)carbonyl]amino 2-methylpropanoate according to Scheme 2. δH (500 MHz, CHLOROFORM-d) 9.21 (1H, d, 1.6 Hz), 8.89 (1H, dd, 4.7, 1.3 Hz), 8.34 (1H, dd, 7.4, 1.4 Hz), 7.53 (1H, dd, 8.2, 4.9 Hz), 2.84 (1H, sept, 7.0 Hz), 1.42 (9H, s), 1.32 (6H, d, 6.9 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09018411B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-cd357bbc7bf3434b89dcbbe757717de3 |
| Source note | uspto-grants-2015_04 |