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HRID1476290

反应详情

EQUATION

反应方程式

HRID 1476290 的结构方程式

REACTANTS

反应物

2
结构：CN(CCO)C(=O)OCc1ccccc1
HCID13279869

Benzyl (2-hydroxyethyl)methylcarbamate

C11H15NO3

2 次

结构：CCN(CCOP(=O)(OC(C)(C)C)OC(C)(C)C)C(=O)OCc1ccccc1
HCID58080156

未命名化合物

PRODUCTS

生成物

1
结构：CN(CCOP(=O)(OC(C)(C)C)OC(C)(C)C)C(=O)OCc1ccccc1
HCID58080112

未命名化合物

收率 67%

PROCEDURE

实验过程

A similar procedure to that described for INTERMEDIATE 48 utilizing benzyl 2-hydroxyethyl(methyl)carbamate (INTERMEDIATE 51, 0.46 g, 2.20 mmol) as starting material was followed, with subsequent purification by column chromatography (ISCO, 12 g silica gel column, eluting with 0→100% EtOAc/hexanes) to give the title product (590 mg, yield: 67%).

WORKUP

后处理

  1. customwas followed, with subsequent purification by column chromatography (ISCO, 12 g silica gel column, eluting with 0→100% EtOAc/hexanes)