Hexane → HCID 131732794, compound

Participants

Reaction Steps

Using 7-methoxy-2-naphthyltrifluoromethanesulfonate (30.63 g, 0.10 mol) and 1-octyne (13.78 g, 0.125 mol), 7-octyn-1-yl-2-methoxynaphthalene was synthesized by the same operation as that in the method for synthesizing 7-decyl-2-methoxynaphthalene according to Example 3, and subjected to column chromatography (silica gel, developed with a mixture of toluene and hexane) to obtain a light yellow oil product of 7-octyn-1-yl-2-methoxynaphthalene (22.9 g, yield of 86%). The obtained 7-octyn-1-yl-2-methoxynaphthalene (total amount) was subjected to catalytic reduction in toluene (213 ml) under a hydrogen atmosphere by adding 10% Pd/C (2.13 g). The obtained product was subjected to column chromatography (silica gel, developed with a mixture of toluene and hexane) to obtain 7-octyl-2-methoxynaphthalene (compound (3)-10, 24.30 g, yield of 90%).

Provenance & Evidence