Hexane → HCID 131732796, compound

Participants

Reaction Steps

Using 7-methoxy-2-naphthyltrifluoromethanesulfonate (30.63 g, 0.10 mol) and 1-dodecyne (20.79 g, 0.125 mol), 7-dodecyn-1-yl-2-methoxynaphthalene was synthesized by the same operation as that in the method for synthesizing 7-decyl-2-methoxynaphthalene according to Example 3, and subjected to column chromatography (silica gel, developed with a mixture of toluene and hexane) to obtain a light yellow oil product of 7-dodecyn-1-yl-2-methoxynaphthalene (32.0 g, quantitative). The obtained 7-dodecyn-1-yl-2-methoxynaphthalene (total amount) was subjected to catalytic reduction in toluene (316 ml) under a hydrogen atmosphere by adding 10% Pd/C (2.11 g). The obtained product was subjected to column chromatography (silica gel, developed with a mixture of toluene and hexane) to obtain 7-dodecyl-2-methoxynaphthalene (compound (3)-14, 31.10 g, yield of 96%).

Provenance & Evidence