HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 67258271, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(Chloromethyl)-2-methyl-1,3-thiazole | HCID 736341 | — |
| Reactant | tert-butyl 4-(2,4-dioxo-6-phenyl-1,4-dihydrothieno[3,2-d]pyrimidin-3(2H)-yl)piperidine-1-carboxylate | HCID 67257815 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67258271 | HCID 67258271 | — |
Reaction Steps
According to GP1 tert-butyl 4-(2,4-dioxo-6-phenyl-1,4-dihydrothieno[3,2-d]pyrimidin-3(2H)-yl)piperidine-1-carboxylate (855 mg; compound B50) is reacted with 4-(chloromethyl)-2-methyl-1,3-thiazole (295 mg; compound D10) in the presence of potassium carbonate (276 mg) in DMF (15 ml). Using WU1 the title compound is obtained as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09018175B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-7bd2a607f9ac4d78a4c7e2d513f2585d |
| Source note | uspto-grants-2015_04 |