Trifluoroacetic acid → HCID 67258448, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of tert-butyl 4-[1-{[2-(methoxymethyl)-2H-tetrazol-5-yl]methyl}-2,4-dioxo-6-phenyl-1,4-dihydrothieno[3,2-d]pyrimidin-3(2H)-yl]piperidine-1-carboxylate (270 mg; compound B24) in DCM (1.69 ml) is slowly added trifluoroacetic acid (0.56 ml) at 0° C. The reaction mixture is stirred for 10 min at 0° C. and for 50 min at RT. All volatiles are removed in vacuo to give the title compound as a solid, which is used for the next step without further purification.

Provenance & Evidence