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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1476656Generated: October 31, 2026

Hydrochloric Acid → HCID 67259261, compound

https://huagongshe.com/reaction/1476656

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 67258349HCID 67258349—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 67259261HCID 67259261—

Reaction Steps

According to the procedure described for compound B92 tert-butyl 4-{1-[(5-ethylthiophen-2-yl)methyl]-2,4-dioxo-6-phenyl-1,4-dihydrothieno[3,2-d]pyrimidin-3(2H)-yl}piperidine-1-carboxylate (1.18 g, compound B73) and a solution of hydrogen chloride in 1,4-dioxane (8.0 ml, 6.8 M) are reacted in 1,4-dioxane (35 ml) to afford the title compound as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09018175B2
Source datasetuspto-grants-2015_04
ORD IDord-b32fe819d9ab4a72a3c1fab079578903
Source noteuspto-grants-2015_04