HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tyramine → HCID 58603606, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tyramine | HCID 5610 | — |
| Reactant | N-[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-N-pyridin-4-ylmethyl-methanesulfonamide | HCID 86603251 | — |
| Product | HCID 58603606 | HCID 58603606 | — |
Reaction Steps
Intermediate 15 was coupled with tyramine following procedure F. LC-MS showed the product had the expected M+H+ of 490. 1H NMR (Varian 300 MHz, CDCl3, shifts relative to the solvent peak at 7.24 ppm) δ 8.4 (d, 2H) 8.2 (d, 1H) 7.9 (m, 2H) 7.4 (m, 2H) 7.2 (d, 2H) 7.0 (d, 2H) 6.9 (d, 1H) 6.7 (d, 2H) 4.4 (s, 2H) 4.3 (s, 2H) 3.6 (m, 2H) 2.9 (m, 5H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732444B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-5cbdf07f11604d03a1faf705a7258623 |
| Source note | uspto-grants-2010_06 |