Methanesulfonyl chloride → HCID 86603253, compound

HRID 14768Notes

Reaction equation

HRID 14768 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([CH:21]=[CH:22][CH:23]=2)[CH2:11][NH:12][CH2:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)[CH:5]=[CH:4][N:3]=1.[CH3:24][S:25](Cl)(=[O:27])=[O:26]>>[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([CH:21]=[CH:22][CH:23]=2)[CH2:11][N:12]([CH2:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)[S:25]([CH3:24])(=[O:27])=[O:26])[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 86603254HCID 86603254, compound

Product 1

HCID 86603253HCID 86603253, compound

Procedure

Intermediate 16 was coupled with methanesulfonyl chloride following procedure D. LC-MS showed the product had the expected M+H+ of 403.

Sources & evidence

ORD record
ord-87d16e1476534c10bff40567bad6b953
Source dataset
uspto-grants-2010_06
Patent number
US07732444B2

Reaction notes

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