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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1476890Generated: November 1, 2026

HCID 136597060, compound → HCID 136597087, compound

https://huagongshe.com/reaction/1476890

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 136597060HCID 136597060—
SolventHydrogen chloride-ethyl acetateHCID 21866389—
ProductHCID 136597087HCID 136597087—

Reaction Steps

A solution of (S)-tert-butyl 3-((7-fluoro-3-(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)isoquinolin-1-yl)amino)pyrrolidine-1-carboxylate (120 mg, 0.29 mmol) in 4M HCl/EtOAc (10 mL) was stirred at RT for 30 minutes. The reaction mixture was concentrated in vacuo to give the title compound, which was used without further purification (100 mg, 100%). ESI-MS m/z [M+H]+ 315.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09402841B2
Source datasetuspto-grants-2016_08
ORD IDord-9d7926d9d3474401872f4516f15e8106
Source noteuspto-grants-2016_08