Hydrazinecarboxylic acid, ethyl ester → HCID 136596926, compound

Participants

Reaction Conditions

Reaction Steps

To crude (S)-tert-butyl 3-((6-cyanopyridin-2-yl)oxy)pyrrolidine-1-carboxylate (1.044 g) in NMP (1.5 mL) was added ethyl hydrazinecarboxylate (0.752 g, 7.22 mmol). The reaction mixture was heated at 175° C. overnight and was subsequently cooled and diluted with EtOAc. The organic phase was washed with saturated aqueous NH4Cl, dried, and concentrated to give the title compound, which was used without further purification.

Provenance & Evidence