Cyclopentanone → HCID 178424653, compound

HRID 1477489Notes

Reaction equation

Br[C:2]1[N:7]=[C:6]([C:8]2[CH2:13][CH2:12][C:11]([CH3:15])([CH3:14])[CH2:10][CH:9]=2)[C:5]([NH:16][C:17]([C:19]2[NH:20][C:21]([C:24]#[N:25])=[CH:22][N:23]=2)=[O:18])=[CH:4][CH:3]=1.[C:26]1(=[O:31])[CH2:30][CH2:29][CH2:28][CH2:27]1>>[CH3:14][C:11]1([CH3:15])[CH2:12][CH2:13][C:8]([C:6]2[C:5]([NH:16][C:17]([C:19]3[NH:23][CH:22]=[C:21]([C:24]#[N:25])[N:20]=3)=[O:18])=[CH:4][CH:3]=[C:2]([C:26]3([OH:31])[CH2:30][CH2:29][CH2:28][CH2:27]3)[N:7]=2)=[CH:9][CH2:10]1

Participants

Reactant 2

HCID 8452Cyclopentanone

HCID 58993772HCID 58993772, compound

Product 1

HCID 178424653HCID 178424653, compound

Procedure

The title compound is prepared from 5-cyano-1H-imidazole-2-carboxylic acid [6-bromo-2-(4,4-dimethyl-cyclohex-1-enyl)-pyridin-3-yl]-amide (as prepared in the previous step) and cyclopentanone according to the procedure in Example 1, step (h).

Sources & evidence

ORD record: ord-da68bab6e98b4be1b933a31d5ffc9d2a
Source dataset: uspto-grants-2016_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09403804B2

Reaction notes

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