HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hydroxy-2-naphthoic acid → (2S,4S)-1-(3,3-Dimethyl-butyl)-4-[(1-hydroxy-naphthalene-2-carbonyl)-amino]-pyrrolidine-2-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hydroxy-2-naphthoic acid | HCID 6844 | — |
| Reactant | (2S,4S)-4-Amino-1-(3,3-dimethyl-butyl)-pyrrolidine-2-carboxylic acid methyl ester | HCID 89776135 | — |
| Product | (2S,4S)-1-(3,3-Dimethyl-butyl)-4-[(1-hydroxy-naphthalene-2-carbonyl)-amino]-pyrrolidine-2-carboxylic acid methyl ester | HCID 71715909 | — |
Reaction Steps
(2S,4S)-1-(3,3-Dimethyl-butyl)-4-[(1-hydroxy-naphthalene-2-carbonyl)-amino]-pyrrolidine-2-carboxylic acid methyl ester was prepared from (2S,4S)-4-amino-1-(3,3-dimethyl-butyl)-pyrrolidine-2-carboxylic acid methyl ester and 1-hydroxy-naphthalene-2-carboxylic acid in an analogous manner to example 1. MS calcd. for C23H31N2O4 [(M+H)+] 399.0, obsd. 399.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403805B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-254e38af9e89430cb4e88938e1b041b3 |
| Source note | uspto-grants-2016_08 |