1-amino-2-naphthoic acid → HCID 71715174, compound

HRID 1477558Notes

Reaction equation

HRID 1477558 reaction equation
[CH3:1][O:2][C:3]([C@@H:5]1[CH2:9][C@H:8]([NH2:10])[CH2:7][N:6]1[CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)=[O:4].[NH2:18][C:19]1[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:22]=[CH:21][C:20]=1[C:29](O)=[O:30]>>[CH3:1][O:2][C:3]([C@@H:5]1[CH2:9][C@H:8]([NH:10][C:29]([C:20]2[CH:21]=[CH:22][C:23]3[C:28](=[CH:27][CH:26]=[CH:25][CH:24]=3)[C:19]=2[NH2:18])=[O:30])[CH2:7][N:6]1[CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)=[O:4]

Participants

3

Reactant 2

HCID 117899421-amino-2-naphthoic acidHCID 89776163(2S,4S)-4-amino-1-cyclohexylmethyl-pyrrolidine-2-carboxylic acid methyl ester

Product 1

HCID 71715174HCID 71715174, compound

Procedure

(2S,4S)-4-[(1-Amino-naphthalene-2-carbonyl)-amino]-1-cyclohexylmethyl-pyrrolidine-2-carboxylic acid methyl ester was prepared from (2S,4S)-4-amino-1-cyclohexylmethyl-pyrrolidine-2-carboxylic acid methyl ester and 1-amino-naphthalene-2-carboxylic acid in an analogous manner to example 1. MS calcd. for C24H32N3O3[(M+H)+] 410, obsd. 410.

Sources & evidence

ORD record
ord-e8ef5250e5e144959fb0320079b9b8a8
Source dataset
uspto-grants-2016_08
Patent number
US09403805B2

Reaction notes

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