HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hydroxy-2-naphthoic acid → (2S,4S)-4-[(1-hydroxy-naphthalene-2-carbonyl)-amino]-2-(5-methyl-oxazol-2-yl)-pyrrolidine-1-carboxylic acid benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hydroxy-2-naphthoic acid | HCID 6844 | — |
| Reactant | (2S,4S)-4-Amino-2-(5-methyl-oxazol-2-yl)-pyrrolidine-1-carboxylic acid benzyl ester | HCID 89768311 | — |
| Product | (2S,4S)-4-[(1-hydroxy-naphthalene-2-carbonyl)-amino]-2-(5-methyl-oxazol-2-yl)-pyrrolidine-1-carboxylic acid benzyl ester | HCID 89768860 | — |
Reaction Steps
(2S,4S)-4-[(1-hydroxy-naphthalene-2-carbonyl)-amino]-2-(5-methyl-oxazol-2-yl)-pyrrolidine-1-carboxylic acid benzyl ester was prepared from (2S,4S)-4-amino-2-(5-methyl-oxazol-2-yl)-pyrrolidine-1-carboxylic acid benzyl ester and 1-hydroxy-naphthalene-2-carboxylic acid in an analogous manner to example 1. MS calcd. for C27H26N3O5 [(M+H)+] 472, obsd. 472.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403805B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-06c8507452034a36b9686dcb58b550ad |
| Source note | uspto-grants-2016_08 |