HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-4-fluorobenzene → HCID 117839600, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-4-fluorobenzene | HCID 9993 | — |
| Reactant | 2-Benzyloctahydropyrrolo[3,4-c]pyrrole | HCID 4454387 | — |
| Reactant | Sodium t-butoxide | HCID 23676156 | — |
| Product | HCID 117839600 | HCID 117839600 | 71% |
Reaction Steps
2-Benzyloctahydropyrrolo[3,4-c]pyrrole (50.0 mg, 0.247 mmol), 1-bromo-4-fluorobenzene (33.0 μL, 0.303 mmol), and sodium tert-butoxide (144 mg, 1.50 mmol) were used to obtain the title compound (52.0 mg, yield 70%) by synthesis in a similar manner to Reference Synthesis Example 23.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403798B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-e50e686dc1d147e8ab5c6397f7643ac6 |
| Source note | uspto-grants-2016_08 |