9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide → 9-{4-[4-(5-chloro-quinoxalin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide

HRID 147771Notes

Reaction equation

HRID 147771 reaction equation
[Cl:27][c:28]1[c:29]2[n:30][cH:31][c:32]([N:38]3[CH2:39][CH2:40][NH:41][CH2:42][CH2:43]3)[n:33][c:34]2[cH:35][cH:36][cH:37]1.[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][Br:24])[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21)([F:25])[F:26]>>[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:41]2[CH2:40][CH2:39][N:38]([c:32]3[cH:31][n:30][c:29]4[c:28]([Cl:27])[cH:37][cH:36][cH:35][c:34]4[n:33]3)[CH2:43][CH2:42]2)[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21)([F:25])[F:26]

Participants

3

Reactant 2

HCID 105264379-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamideHCID 126864275-Chloro-2-piperazin-1-yl-quinoxaline

Product 1

HCID 226362349-{4-[4-(5-chloro-quinoxalin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide

Sources & evidence

ORD record
ord-fbef7ff4cda649e49be7a85a3c6883db
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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