Benzoyl isothiocyanate → HCID 86688406, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of compound 17 (5.0 g, 33.1 mmol) in 40 mL of acetone at 0° C. was added dropwise benzoyl isothiocynate (5.4 g, 33.1 mmol). The reaction mixture was gradually warmed up and stirred in an oil bath of 60° C. until TLC indicated there was no starting material remained. Concentration of the reaction mixture on rotavapor gave a yellow solid, which was further recrystallized in ethyl acetate to yield the desired product 18.

Provenance & Evidence