HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(5-Methyl-1,2,4-oxadiazol-3-yl)cyclobutan-1-amine hydrochloride → 6-(3-Chloro-phenyl)-5-cyclopropyl-pyrazine-2-carboxylic acid [1-(5-methyl-[1,2,4]oxadiazol-3-yl)-cyclobutyl]-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(5-Methyl-1,2,4-oxadiazol-3-yl)cyclobutan-1-amine hydrochloride | HCID 42959052 | — |
| Edukt | 6-(3-Chloro-phenyl)-5-cyclopropyl-pyrazine-2-carboxylic acid | HCID 86682318 | — |
| Produkt | 6-(3-Chloro-phenyl)-5-cyclopropyl-pyrazine-2-carboxylic acid [1-(5-methyl-[1,2,4]oxadiazol-3-yl)-cyclobutyl]-amide | HCID 71525482 | — |
Reaktionsschritte
The title compound was synthesized in analogy to Example 1e, using 6-(3-chloro-phenyl)-5-cyclopropyl-pyrazine-2-carboxylic acid and 1-(5-methyl-1,2,4-oxadiazol-3-yl)-cyclobutanamine hydrochloride (CAN 1170897-128-5) as starting materials, and isolated (43 mg, 58%) as white solid; MS (EI): 410.2 (M+H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09403808B2 |
| Quelldatensatz | uspto-grants-2016_08 |
| ORD ID | ord-6634f48bb9ce48e3a6c870f63cf94252 |
| Quellennotiz | uspto-grants-2016_08 |