HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-Methyl 2-amino-3-cyclopropylpropanoate HCl → HCID 71525766, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-Methyl 2-amino-3-cyclopropylpropanoate HCl | HCID 66593107 | — |
| Reactant | 5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid | HCID 86682331 | — |
| Product | HCID 71525766 | HCID 71525766 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 6, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g) and (αS)-α-amino-cyclopropanepropanoic acid methyl ester hydrochloride (1:1) (CAN 206438-31-5) as starting materials, and isolated (80 mg, 75%) as yellow oil; LC-MS (UV peak area, ESI) 100%, 360.1920 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403808B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-6fcc3b797d0d47579f741062974fe7d4 |
| Source note | uspto-grants-2016_08 |