HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1-Aminocyclohexyl)methanol hydrochloride → HCID 71526577, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1-Aminocyclohexyl)methanol hydrochloride | HCID 20211929 | — |
| Reactant | 5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid | HCID 86682331 | — |
| Product | HCID 71526577 | HCID 71526577 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 69, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g, 50 mg, 0.214 mmol) and (1-amino-cyclohexyl)-methanol hydrochloride (CAN 5460-68-4, 22.8 mg, 0.17 mmol) as starting materials and isolated (46 mg, 62.32%) as white solid; LC-MS (UV peak area, ESI) 96.49%, 346.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403808B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-65c876e4bbd946b49d1006bcee6657c5 |
| Source note | uspto-grants-2016_08 |