Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1477822Generated: November 1, 2026

5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid → HCID 71526659, compound

https://huagongshe.com/reaction/1477822

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acidHCID 86682331—
ReactantHCID 86682342HCID 86682342—
ProductHCID 71526659HCID 71526659—

Reaction Steps

The title compound was synthesized in analogy to Example 69, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g, 50 mg, 0.21 mmol) and 2-amino-3-cyclobutyl-N,N-dimethyl-propionamide (54.48 mg, 0.32 mmol) as starting materials and isolated (20 mg, 24.3%) as white solid; LC-MS (UV peak area, ESI) 100%, 387.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09403808B2
Source datasetuspto-grants-2016_08
ORD IDord-8e8751e1a79240e291e75817a28fca09
Source noteuspto-grants-2016_08