HCID 118390116, compound → HCID 118389998, compound

Participants

Reaction Steps

To a solution of tert-butyl 3,3-diallyl-2-oxopiperidine-1-carboxylate (4.74 g, 16.9 mmol) in dichloromethane (20 mL) was added Grubbs first generation catalyst (711 mg, 0.85 mmol). The reaction mixture was stirred at rt for 4 h and concentrated in vacuo. The residue was purified by silica gel column chromatography (EtOAc/PE (v/v)=1/9) to give the title compound as a white solid (3.61 g, 85%).

Provenance & Evidence