HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ninhydrin → 6-Carboxyfluorescein succinimidyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ninhydrin | HCID 10236 | — |
| Reactant | 6-Carboxyfluorescein | HCID 76806 | — |
| Reactant | HCID 21988380 | HCID 21988380 | — |
| Product | 6-Carboxyfluorescein succinimidyl ester | HCID 2762614 | — |
Reaction Steps
The resin was treated with 2 equivalents 6-FAM-NHS in 1% DIEA/N,N-dimethylformamide and stirred or shaken at ambient temperature overnight. When complete, the resin was drained, washed thrice with N,N-dimethylformamide, thrice with (1×DCM and 1×methanol) and dried to provide an orange resin that was negative by ninhydrin test.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403822B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-f024ce16d9ee42cd8fd7dc9cf4c3a5af |
| Source note | uspto-grants-2016_08 |