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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1478368Generated: November 2, 2026

HCID 68297022, compound → HCID 86696761, compound

https://huagongshe.com/reaction/1478368

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68297022HCID 68297022—
ReactantMethyl 8-chloro-1-cyclopropyl-9-methyl-4-oxo-quinolizine-3-carboxylateHCID 86696543—
ProductHCID 86696761HCID 8669676139.1%

Reaction Steps

Methyl 8-(3-methyl-4-(methylamino)phenyl)-1-cyclopropyl-9-methyl-4-oxo-4H-quinolizine-3-carboxylate was prepared according to General Procedure A from methyl 8-chloro-1-cyclopropyl-9-methyl-4-oxo-4H-quinolizine-3-carboxylate (100 mg, 0.34 mmol) and N,2-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (101.5 mg, 0.41 mmol). The residue was rinsed with DCM and dried in a vacuum stove to afford the title compound as a yellow solid (50 mg, 39%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09403818B2
Source datasetuspto-grants-2016_08
ORD IDord-e1111925bc3441d28ac31cbb5aef26ca
Source noteuspto-grants-2016_08