N-Methoxy-N-methylisonicotinamide → HCID 118005621, compound

HRID 1478511Notes

Reaction equation

HRID 1478511 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:11]=[CH:12][N:13]=1)[C:5](N(OC)C)=[O:6].CON(C)C(=O)C1C=CN=CC=1.ClC1C(C2C=CC=CC=2)=C(Cl)C2C(=CC=C(C([C:52]3[N:56]([CH3:57])[CH:55]=[N:54][CH:53]=3)(C3C=CN=CC=3)O)C=2)N=1>>[F:1][C:2]1[CH:3]=[C:4]([C:5]([C:55]2[N:56]([CH3:57])[CH:52]=[CH:53][N:54]=2)=[O:6])[CH:11]=[CH:12][N:13]=1

Participants

4

Reactant 3

HCID 3817473N-Methoxy-N-methylisonicotinamideHCID 44818651HCID 44818651, compoundHCID 74222810HCID 74222810, compound2×

Product 1

HCID 118005621HCID 118005621, compound

Procedure

The title compound was prepared using 2-fluoro-N-methoxy-N-methylisonicotinamide (Intermediate 28: step a) in place of N-methoxy-N-methylisonicotinamide (Intermediate 25: step a) according to the procedure described in Intermediate 25: step b.

Sources & evidence

ORD record
ord-483d784dfda1494cb4412d666b6875d6
Source dataset
uspto-grants-2016_08
Patent number
US09403816B2

Reaction notes

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