HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → (2R,3R)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 2,3-diethyl (2R,3R)-oxirane-2,3-dicarboxylate | HCID 2733646 | — |
| Product | (2R,3R)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid | HCID 13150798 | 73.5% |
Reaction Steps
Followed general procedure for 4 using the following quantities: 3b (15.2 g, 81 mmol): KOH (4.53 g, 81 mmol, in EtOH [50 ml]); yielded 5 as a colorless oil (9.5 g, 73.5%). 1H NMR (CDCl3, 400 MHz): δ 7.57 (br, 1H); 4.35-4.24 (m, 2H); 3.73 (s, 1H); 3.72 (s, 1H); 1.36-1.32 (t 3H). 13C NMR (CDCl3, 100 MHz): 171.61, 166.40, 62.45, 52.20, 51.45, 13.89.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403843B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-f22de3460e6149169b5dff18a55d6d15 |
| Source note | uspto-grants-2016_08 |