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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1478786Generated: October 26, 2026

tert-Butyl 4-hydroxybenzoate → (R)-4-((5-(4-chlorophenyl)-1-ethyl-4-(3-(4-(4-(4-((4-(4-hydroxypiperidin-1-yl)-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenylsulfonamido)phenyl)piperazin-1-yl)phenyl)-2-methyl-1H-pyrrole-3-carbonyl)oxy)benzoic acid

https://huagongshe.com/reaction/1478786

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 4-hydroxybenzoateHCID 117640—
Reactant5-(4-chlorophenyl)-1-ethyl-4-[3-[4-[4-[[4-[[(2R)-4-(4-hydroxypiperidin-1-yl)-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylamino]phenyl]piperazin-1-yl]phenyl]-2-methylpyrrole-3-carboxylic acidHCID 71456995—
Product(R)-4-((5-(4-chlorophenyl)-1-ethyl-4-(3-(4-(4-(4-((4-(4-hydroxypiperidin-1-yl)-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenylsulfonamido)phenyl)piperazin-1-yl)phenyl)-2-methyl-1H-pyrrole-3-carbonyl)oxy)benzoic acidHCID 90279494—

Reaction Steps

6 was prepared from BM-957 and tert-butyl 4-hydroxybenzoate according general procedure IV. MS (ESI): m/z 1186.00 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09403856B2
Source datasetuspto-grants-2016_08
ORD IDord-88cd3edcca4b43a6aba2693a24655e3e
Source noteuspto-grants-2016_08