Dichloromethane → 1-(3-acetylamino-4-hydroxybenzyl)-4-[[N-(2-(tert-butoxycarbonylamino)-4,5-difluorobenzoyl)glycyl]aminomethyl]piperidine
Reaction equation
[CH3:40][C:41](=[O:42])[O:43][C:44](=[O:45])[CH3:46].[Cl:47][CH2:48][Cl:49].[NH2:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[CH2:7][CH2:8][CH:9]([CH2:12][NH:13][C:14]([CH2:15][NH:16][C:17]([c:18]3[c:19]([NH:26][C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[cH:20][c:21]([F:25])[c:22]([F:24])[cH:23]3)=[O:34])=[O:35])[CH2:10][CH2:11]2)[cH:36][cH:37][c:38]1[OH:39]>>[NH:1]([c:2]1[cH:3][c:4]([CH2:5][N:6]2[CH2:7][CH2:8][CH:9]([CH2:12][NH:13][C:14]([CH2:15][NH:16][C:17]([c:18]3[c:19]([NH:26][C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[cH:20][c:21]([F:25])[c:22]([F:24])[cH:23]3)=[O:34])=[O:35])[CH2:10][CH2:11]2)[cH:36][cH:37][c:38]1[OH:39])[C:41]([CH3:40])=[O:42]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-cd60605730364fd68bf7a45ad87ea3d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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