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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1478952Generated: November 1, 2026

Ingenol → Ingenol Mebutate

https://huagongshe.com/reaction/1478952

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIngenolHCID 442042—
SolventDimethyl SulfoxideHCID 679—
ProductIngenol MebutateHCID 6918670—

Reaction Steps

(NOTE: Ingenol purity was calculated as 84.18% by quantitative 1H NMR. As ingenol-3-angelate, PEP015, PEP025 and ingenol-3,20-diangelate were provided as solutions in DMSO, purity was not calculated but assumed to be 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09404131B2
Source datasetuspto-grants-2016_08
ORD IDord-bed63d513b8146a3988c7373bcc283e6
Source noteuspto-grants-2016_08